Obesity and lung cancer-a narrative review.

ABSTRACT:

Background and objective

A highly nuanced relationship exists between obesity and lung cancer. The association between obesity and lung cancer risk/prognosis varies depending on age, gender, race, and the metric used to quantify adiposity. Increased body mass index (BMI) is counterintuitively associated with decreased lung cancer incidence and mortality, giving rise to the term 'obesity paradox'. Potential explanations for this paradox are BMI being a poor measure of obesity, confounding by smoking and reverse causation. A literature search of this topic yields conflicting conclusions from various authors. We aim to clarify the relationship between various measures of obesity, lung cancer risk, and lung cancer prognosis.

Methods

The PubMed database was searched on 10 August

SUBMITTER: Vedire Y 

PROVIDER: S-EPMC10267921 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature