Evaluation of serum and cerebrospinal fluid biomarkers after vaccination against SARS-CoV-2.

ABSTRACT:

Objective

Vaccines are a major achievement of science, and new vaccines against SARS-CoV-2 are protecting the entire population from a life-threatening infection. Although several neurological complications or worsening of pre-existing neurological conditions after vaccination have been observed, whether a biological plausibility exist between new vaccines against-SARS-CoV-2 and neurological consequences is unclear. The aim of this study is to evaluate whether vaccines against SARS-CoV-2 induce systemic or cerebrospinal fluid alterations in patients with neurological disorders.

Methods

Patients who underwent lumbar puncture (LP) between February 2021 and October 2022 were enrolled. Serum C-reactive protein (CRP), neutrophil to lymphocyte ratio (NLR), cerebrospinal fluid tota

SUBMITTER: Iacono S 

PROVIDER: S-EPMC10270270 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature