Glomerular filtration rate estimated by differing measures and risk of all-cause mortality among Chinese individuals without or with diabetes: A nationwide prospective study.

ABSTRACT:

Background

Whether estimated glomerular filtration rates (eGFRs) by differing biomarkers are differentially associated with mortality or whether the associations differ by diabetes status remains unclear, especially in Chinese population.

Methods

We included 6995 participants without diabetes (mean age: 60.4 years) and 1543 with diabetes (mean age: 61.8 years). Each eGFR measure was divided into normal (≥90 mL/min/1.73 m² ), modestly declined (60 to <90 mL/min/1.73 m² ), and chronic kidney disease (CKD) (<60 mL/min/1.73 m² ) groups. Cox proportional hazards models were used to estimate hazard ratio (HR) of all-cause mortality associated with each eGFR.

Results

Over a follow-up of 7 years, 677 and 215 deaths occurred among individuals w

SUBMITTER: Liu YJ 

PROVIDER: S-EPMC10270745 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature