Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis.

ABSTRACT:

Objective

Colorectal cancer shows large incidence variations worldwide that have been attributed to different dietary factors. We conducted a meta-analysis on the relationship between garlic consumption and colorectal cancer risk.

Design

We systematically reviewed publications obtained by searching ISI Web of Knowledge, MEDLINE and EMBASE literature databases. We extracted the risk estimate of the highest and the lowest reported categories of intake from each study and conducted meta-analysis using a random-effects model.

Results

The pooled analysis of all fourteen studies, seven cohort and seven case-control, indicated that garlic consumption was not associated with colorectal cancer risk (OR=0·93; 95 % CI 0·82, 1·06, P=0·281; I 2=83·6 %, P≤0·001). Separate analyses

SUBMITTER: Chiavarini M 

PROVIDER: S-EPMC10270922 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature