Leaf concentrate compared with skimmed milk as nutritional supplementation for HIV-infected children: a randomized controlled trial in Burundi.

ABSTRACT:

Objective

The effectiveness of leaf concentrate powder (LCP) as a nutritional supplement was established in trials conducted among adolescent girls and pregnant women in India. Here we evaluate LCP, compared with skimmed milk powder (SMP), as a supplement for antiretroviral-naïve children living with HIV in a sub-Saharan African country.

Design

Randomized controlled, two-arm, 6-month trial comparing effects of isoproteic (5 g) LCP (10 g daily) and SMP (15 g daily) on HIV-1 viral load, CD4+ cell count/percentage, weight/height-for-age, general blood parameters, diarrhoea, respiratory and HIV-related opportunistic infections.

Setting

Bujumbura and Kirundo, Burundi.

Subjects

Eighty-three HIV-positive, antiretroviral-naïve children aged 5-14 years: median (range) C

SUBMITTER: Collin SM 

PROVIDER: S-EPMC10271179 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature