Genetic and environmental factors associated with vitamin B12 status in Amazonian children.

ABSTRACT:

Objective

To evaluate the prevalence of vitamin B12 deficiency and factors associated with vitamin B12 status in Amazonian children.

Design

Genetic risk score (GRS), socio-economic and nutritional status, and morbidity data were the independent variables used in multiple linear regression models to evaluate factors associated with vitamin B12 status in a population-based cross-sectional study. GRS was created by summing a number of known risk alleles for low serum vitamin B12.

Setting

Acrelândia, western Brazilian Amazon.

Subjects

Children (n 988) aged <10 years.

Results

Overall prevalence of vitamin B12 deficiency (<150 pmol/l) was 4·2 (95 % CI 3·0, 5·6) % and was highest in children aged <24 months: 13·6 (95 % CI % 8·8, 19·7) %. For children <24 months

SUBMITTER: Cobayashi F 

PROVIDER: S-EPMC10271475 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature