Clinical features do not identify risk of progression from isolated postcapillary pulmonary hypertension to combined pre‐ and postcapillary pulmonary hypertension

ABSTRACT: Abstract Pulmonary hypertension is a common sequelae of left heart failure and may present as isolated postcapillary pulmonary hypertension (Ipc‐PH) or combined pre‐ and postcapillary pulmonary hypertension (Cpc‐PH). Clinical features associated with progression from Ipc‐PH to Cpc‐PH have not yet been described. We extracted clinical data from patients who underwent right heart catheterizations (RHC) on two separate occasions. Ipc‐PH was defined as mean pulmonary pressure >20 mmHg, pulmonary capillary wedge pressure >15 mmHg, and pulmonary vascular resistance (PVR) < 3 WU. Progression to Cpc‐PH required an increase in PVR to ≥3 WU. We performed a retrospective cohort study with repeated assessments comparing subjects that progressed to Cpc‐PH to subjects that remained with Ipc‐PH. Of 153 p

SUBMITTER: Babu G 

PROVIDER: S-EPMC10271598 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature