Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.

ABSTRACT:

Objective

To develop and validate a novel FFQ to assess the daily intake of four methyl-group donors (methionine, choline, betaine and folate).

Design

The relative validity of the FFQ was assessed by comparison with 7 d estimated diet records (n 80) and its reproducibility was evaluated by repeated administrations 6 weeks apart (n 92). Paired Student t tests were used to compare group means and de-attenuated intra-class correlations to investigate the ability of the FFQ to rank individuals according to their methyl-group donor intake. De-attenuated intra-class correlation coefficients were calculated between the test and reference method for methionine, choline, betaine, folate and the sum of methyl-group donors. The weighted kappa (κ w) was calculated as a measure of tertil

SUBMITTER: Pauwels S 

PROVIDER: S-EPMC10271734 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature