The association between serum lipids and colorectal neoplasm: a systemic review and meta-analysis.

ABSTRACT:

Objective

There have been inconsistent results published regarding the relationship between dyslipidaemia and an increased risk of colorectal neoplasia (CRN), including colorectal adenoma (CRA) and colorectal cancer (CRC). We conducted a meta-analysis to explore the relationship between dyslipidaemia and CRN.

Design

We identified studies by performing a literature search using PubMed, EMBASE and the Science Citation Index through October 2013.

Setting

We analysed thirty-three independent studies reporting the association between CRN and at least one of the selected lipid components, including total cholesterol (TC), TAG, HDL-cholesterol (HDL-C) and LDL-cholesterol (LDL-C).

Subjects

CRN cases (n 21 809) were identified.

Results

Overall, people with high l

SUBMITTER: Tian Y 

PROVIDER: S-EPMC10271749 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature