Oligodendrogliomas tend to infiltrate the frontal aslant tract, whereas astrocytomas tend to displace it.

ABSTRACT:

Introduction

MR-tractography is increasingly used in neurosurgical practice to evaluate the anatomical relationships between glioma and nearby subcortical tracts. In some patients, the subcortical tracts seem displaced by the glioma, while in other patients, the subcortical tracts seem infiltrated without displacement. At this point, it is unknown whether these different patterns are related to tumor type. The aim of this exploratory study was to investigate whether tumor type is related to the spatial tractography pattern of the frontal aslant tract (FAT) in low-grade gliomas (LGGs).

Methods

In 64 IDH-mutated LGG patients, the FAT was generated using a pipeline for automatic tractography. In 41 patients, the glioma adjoined the FAT, and four blinded reviewers independently

SUBMITTER: Landers MJF 

PROVIDER: S-EPMC10271893 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature