Fraction optimization for hybrid proton-photon treatment planning.

ABSTRACT:

Background

Hybrid proton-photon radiotherapy (RT) can provide better plan quality than proton or photon only RT, in terms of robustness of target coverage and sparing of organs-at-risk (OAR).

Purpose

This work develops a hybrid treatment planning method that can optimize the number of proton and photon fractions as well as proton and photon plan variables, so that the hybrid plans can be clinically delivered day-to-day using either proton or photon machine.

Methods

In the new hybrid treatment planning method, the total dose distribution (sum of proton dose and photon dose) is optimized for robust target coverage and optimal OAR sparing, by jointly optimizing proton spots and photon fluences, while the target dose uniformity is also enforced individually on both proton

SUBMITTER: Li W 

PROVIDER: S-EPMC10271913 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature