The Relationship of Kidney Function, Cardiovascular Morbidity, and All-Cause Mortality: a Prospective Primary Care Cohort Study.

ABSTRACT:

Background

Lower-than-normal estimated glomerular filtration rate (eGFR) is associated with the risk for all-cause mortality and adverse cardiovascular events. In this regard, the role of higher-than-normal eGFR is still controversial.

Objective

Investigate long-term clinical consequences across the levels of eGFR calculated by the creatinine-based Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation among apparently healthy cardiovascular risk subjects.

Design

Prospective study.

Participants

Participants (n=1747) of a population-based screening and intervention program for cardiovascular risk factors in Finland during the years 2005-2007.

Main measures

Cardiovascular morbidity and all-cause mortality.

Key results

Over the 14-year

SUBMITTER: Korhonen PE 

PROVIDER: S-EPMC10271946 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature