The First Genomic Characterization of the Chikungunya Virus in Saudi Arabia.

ABSTRACT:

Background

Chikungunya is an arboviral infection caused by the Chikungunya virus (CHIKV) transmitted to humans by mosquitoes of Aedes spp. CHIKV has been confined to African countries and South-East Asia up to 2004, but since then, the pathogen has become more global, and its high morbidity rate has become more visible. Saudi Arabia is not an endemic region of CHIKV, and the virus's origin is not yet fully understood. This study aimed to characterize the genome of CHIKV from samples detected in Jeddah in 2018.

Method

Twenty-two sets of primers were designed to amplify near-full length genome of CHIKV. RT-PCR was conducted from clinical samples. Two samples were used for studying near complete genome sequence while the remaining samples were used to study the E1 gene. Differe

SUBMITTER: Alguridi HI 

PROVIDER: S-EPMC10272072 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature