Cannabis self-administration in the human laboratory: a scoping review of ad libitum studies.

ABSTRACT: Cannabis self-administration studies may be helpful for identifying factors that influence cannabis consumption and subjective response to cannabis. Additionally, these paradigms could be useful for testing novel pharmacotherapies for cannabis use disorder. This scoping review aims to summarize the findings from existing ad libitum cannabis self-administration studies to determine what has been learned from these studies as well as their limitations. We examined studies that specifically examined cannabis smoking, focusing on subjective response and self-administration behavior (e.g., smoking topography). A systematic search was conducted using PubMed and Embase from inception to October 22, 2022. Our search strategy identified 26 studies (total N = 662, 79% male) that met our eligibility

SUBMITTER: Xiao KB 

PROVIDER: S-EPMC10272254 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature