Tele-supervised home-based transcranial alternating current stimulation (tACS) for Alzheimer's disease: a pilot study.

ABSTRACT:

Background

Over 55 million people worldwide are currently diagnosed with Alzheimer's disease (AD) and live with debilitating episodic memory deficits. Current pharmacological treatments have limited efficacy. Recently, transcranial alternating current stimulation (tACS) has shown memory improvement in AD by normalizing high-frequency neuronal activity. Here we investigate the feasibility, safety, and preliminary effects on episodic memory of an innovative protocol where tACS is administered within the homes of older adults with AD with the help of a study companion (HB-tACS).

Methods

Eight participants diagnosed with AD underwent multiple consecutive sessions of high-definition HB-tACS (40 Hz, 20-min) targeting the left angular gyrus (AG), a key node of the memory network. T

SUBMITTER: Cappon D 

PROVIDER: S-EPMC10272342 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature