Effects of destruxin A on hemocytes of the domestic silkworm, Bombyx mori.

ABSTRACT:

Introduction

Destruxin A (DA) is a mycotoxin isolated from the entomopathogenic fungus Metarhizium anisopliae which has demonstrated inhibitory activity against various insect species. However, the mechanism of inhibition on target sites in insects remains unknown.

Methods

In this research, the dose-response relationship between DA and morphological changes in body tissues and organs of domestic silkworm, Bombyx mori, were investigated by histopathological methods to identify the target sites that responded to DA.

Results and discussion

The results showed that responses of individual tissues and organs varied with DA dosage and treatment time. At low doses (i.e., 0.01μg/g), the hemocytes were the most sensitive to DA with morphological changes apparent a

SUBMITTER: Yin F 

PROVIDER: S-EPMC10272401 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature