Whole-genome sequencing analysis of Klebsiella aerogenes among men who have sex with men in Guangzhou, China.

ABSTRACT: Klebsiella aerogenes is a common infectious bacterium that poses a threat to human health. Nevertheless, there are limited data on the population structure, genetic diversity, and pathogenicity of K. aerogenes, especially among men who have sex with men (MSM). The present study aimed to clarify the sequence types (STs), clonal complexes (CCs), resistance genes, and virulence factors of popular strains. Multilocus sequence typing was used to describe the population structure of K. aerogenes. The Virulence Factor Database and Comprehensive Antibiotic Resistance Database were used to assess the virulence and resistance profiles. In this study, next-generation sequencing was performed on nasal swabs specimens collected in an HIV Voluntary Counseling Testing outpatient depa

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC10272549 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature