Gut microbiota-derived metabolite trimethylamine-N-oxide and stroke outcome: a systematic review.

ABSTRACT:

Introduction

The relationship between baseline trimethylamine N-oxide (TMAO) levels and stroke outcomes remains unclear. Therefore, this systematic review aimed to summarize the existing relevant research.

Methods

We searched for studies on the association between baseline plasma levels of TMAO and stroke outcomes in the PubMed, EMBASE, Web of Science, and Scopus databases from their inception to 12 October 2022. Two researchers independently reviewed the studies for inclusion and extracted the relevant data.

Results

Seven studies were included in the qualitative analysis. Among them, six studies reported the outcome of acute ischemic stroke (AIS) and one study of intracerebral hemorrhage (ICH), respectively. Furthermore, no study reported the outcome of subarachnoid

SUBMITTER: Zhang P 

PROVIDER: S-EPMC10272813 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature