Dataset Information

A novel assessment of participation and executive functions (A-PEX) for traumatic brain injury: a validity study.

ABSTRACT:

Background

Executive function deficits are a main cause of participation restrictions post-traumatic brain injury (TBI). Assessing executive functions through actual daily participation may provide valuable information for treatment planning and progress.

Aim

This study aimed to validate the Assessment of Participation and Executive Functions (A-PEX), a tool for evaluating executive function deficits through actual participation in the inpatient rehabilitation context during the subacute phase following TBI.

Design

A cross-sectional with a longitudinal component.

Setting

Inpatient rehabilitation facility.

Population

This study included 56 participants divided into two groups: 30 with orthopedic or spinal cord injuries and 26 with TBI.

Methods

Internal consistency was evaluated by Cronbach's alpha, and test-retest reliability was assessed using interclass correlation coefficients. Known-group construct validity was examined by comparing the A-PEX scores between the two groups, and A-PEX convergent construct validity for patients with TBI was examined using correlations between scores on the A-PEX, Multiple Errands Test-hospital version (MET-HV), and Color Trail Test (CTT).

Results

Cronbach's alpha coefficients for the A-PEX domains ranged between 0.83 and 0.96, indicating good-to-excellent internal consistency. Interclass correlations calculated for the control group indicated moderate test-retest reliability for most A-PEX components. Participants with TBI scored significantly lower than those with orthopedic or spinal cord injury for all A-PEX components (P<0.001). Within the TBI group, significant moderate-to-strong correlations were found between all A-PEX components and the MET-HV (0.52ConclusionsThe findings provide evidence for the initial reliability and validity of the A-PEX as a measure of post-TBI executive functions.

Clinical rehabilitation impact

By evaluating actual everyday participation, the A-PEX provides valuable clinical insight into the interrelationship between executive functions and participation in the post-TBI subacute phase.

SUBMITTER: Eliav R

PROVIDER: S-EPMC10272933 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Publications

A novel assessment of participation and executive functions (A-PEX) for traumatic brain injury: a validity study.

Eliav Rotem R Lugassy Yael Y Kizony Rachel R

European journal of physical and rehabilitation medicine 20230421 3

<h4>Background</h4>Executive function deficits are a main cause of participation restrictions post-traumatic brain injury (TBI). Assessing executive functions through actual daily participation may provide valuable information for treatment planning and progress.<h4>Aim</h4>This study aimed to validate the Assessment of Participation and Executive Functions (A-PEX), a tool for evaluating executive function deficits through actual participation in the inpatient rehabilitation context during the s ...[more]

PMID: 37083100

Similar Datasets

Project description:ImportanceExecutive functions are critical for school and social success. Although these functions are adversely affected by pediatric traumatic brain injury (TBI), recovery patterns are not well established.ObjectiveTo examine 3-year trajectories of selected children's executive functions after TBI.Design, setting, and participantsThis prospective cohort study was conducted from January 22, 2013, to September 30, 2015, with 3-year follow-up at the level I pediatric trauma centers Primary Children's Hospital in Salt Lake City, Utah and Children's Memorial Hermann Hospital in Houston, Texas. Study participants included children aged 2 to 15 years with TBI or orthopedic injury (OI) who were treated at the participating hospitals. Children were consecutively recruited and stratified by injury severity and age group. A total of 625 children consented and completed a baseline survey; 559 (89%) children completed at least 1 follow-up and composed the analysis cohort. It was hypothesized that recovery would differ by injury severity, age at injury, and sex. Data analyses were performed from June to October 2019.Main outcomes and measuresGrowth curve models examined the pattern of change in the Emotional Control, Inhibit, Working Memory, and Plan-Organize subscales of the Behavior Rating Inventory of Executive Function (BRIEF) or BRIEF-Preschool. For all BRIEF subscales, higher scores indicate worse symptoms, and a score of 65 or greater represents clinical impairment.ResultsA total of 559 children (mean [SD] age, 8.6 [4.4] years; 356 boys [64%], 328 non-Hispanic White children [59%]) were included in the study: 155 (28%) children had mild TBI, 162 (29%) had complicated mild or moderate TBI, 90 (16%) had severe TBI, and 152 (27%) had OI. Growth curve trajectories varied by BRIEF subscale and injury severity. Overall, children with TBI did not return to their preinjury baseline, with a stepwise worsening of each outcome at 36 months by TBI severity compared with OI. Among children with severe TBI, trajectories accelerated fastest, indicating increased problems, from injury to 12 months for the Emotional Control (9.0 points; 95% CI, 6.0-11.9 points), Inhibit (3.6 points; 95% CI, 1.6-5.6 points), and Working Memory (7.0 points; 95% CI, 4.1-9.9 points) subscales. Their trajectories plateaued, with a secondary acceleration before 36 months for the Emotional Control and Working Memory subscales. Children with mild TBI had worse 36-month scores on all subscales except Inhibit compared with OI. Recovery patterns were similar for boys and girls.Conclusions and relevanceIn this longitudinal cohort study of children with TBI, trajectory analysis revealed that some children worsen after a recovery plateau, suggesting a need for longitudinal reassessment beyond 1 year postinjury.

Project description:BackgroundSome individuals who sustain traumatic brain injuries (TBIs) continue to experience significant cognitive impairments chronically (months to years post injury). Many tests of executive function are insensitive to these executive function impairments, as such impairments may only appear during complex daily life conditions. Daily life often requires us to divide our attention and focus on abstract goals. In the current study, we compare the effects of two 1-month electronic cognitive rehabilitation programs for individuals with chronic TBI. The active program (Expedition: Strategic Advantage) focuses on improving goal-directed executive functions including working memory, planning, long-term memory, and inhibitory control by challenging participants to accomplish life-like cognitive simulations. The challenge level of the simulations increases in accordance with participant achievement. The control intervention (Expedition: Informational Advantage) is identical to the active program; however, the cognitive demand level is capped, preventing participants from advancing beyond a set level. We will evaluate these interventions with a military veteran TBI population.Methods/designOne hundred individuals will be enrolled in this double-blinded clinical trial (all participants and testers are blinded to condition). Each individual will be randomly assigned to one of two interventions. The primary anticipated outcomes are improvement of daily life cognitive function skills and daily life functions. These are measured by a daily life performance task, which tests cognitive skills, and a survey that evaluates daily life functions. Secondary outcomes are also predicted to include improvements in working memory, attention, planning, and inhibitory control as measured by a neuropsychological test battery. Lastly, neuroimaging measures will be used to evaluate changes in brain networks supporting cognition pre and post intervention.DiscussionWe will test whether electronically delivered cognitive rehabilitation aimed at improving daily life functional skills will provide cognitive and daily life functional improvements for individuals in the chronic phase of TBI recovery (greater than 3 months post injury). We aim to better understand the cognitive processes involved in recovery and the characteristics of individuals most likely to benefit. This study will also address the potential to observe generalizability or to transfer from a software-based cognitive training tool toward daily life improvement.Trial registrationClinicalTrials.gov, NCT03704116 . Retrospectively registered on 12 Oct 2018.

Dataset Information

A novel assessment of participation and executive functions (A-PEX) for traumatic brain injury: a validity study.

Background

Aim

Design

Setting

Population

Methods

Results

Clinical rehabilitation impact

Publications

A novel assessment of participation and executive functions (A-PEX) for traumatic brain injury: a validity study.

Similar Datasets

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