Total energy expenditure as assessed by doubly labeled water and all-cause mortality in a cohort of postmenopausal women.

ABSTRACT:

Background

The association of TEE with all-cause mortality is uncertain, as is the dependence of this association on age.

Objectives

To examine the association between TEE and all-cause mortality, and its age interaction, in a Women's Health Initiative (WHI) cohort of postmenopausal United States women (1992-present).

Methods

A cohort of 1131 WHI participants having DLW TEE assessment of ∼10.0 y (median) following WHI enrollment with ∼13.7 y (median) of subsequent follow-up, was used to study the EE associations with all-cause mortality. To enhance the comparability of TEE and total EI, key analyses excluded participants having >5% weight change between WHI enrollment and DLW assessment. The influence of participant age on mortality associations was examined, as was t

SUBMITTER: Prentice RL 

PROVIDER: S-EPMC10273089 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature