Proteins from toad's parotoid macroglands: do they play a role in gland functioning and chemical defence?

ABSTRACT:

Background

Parotoid gland secretion of bufonid toads is a rich source of toxic molecules that are used against predators, parasites and pathogens. Bufadienolides and biogenic amines are the principal compounds responsible for toxicity of parotoid secretion. Many toxicological and pharmacological analyses of parotoid secretions have been performed, but little is known about the processes related to poison production and secretion. Therefore, our aim was to investigate protein content in parotoids of the common toad, Bufo bufo, to understand the processes that regulate synthesis and excretion of toxins as well as functioning of parotoid macroglands.

Results

Applying a proteomic approach we identified 162 proteins in the extract from toad's parotoids that were classified into 1

SUBMITTER: Kowalski K 

PROVIDER: S-EPMC10273630 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature