Reconstruction of SARS-CoV-2 outbreaks in a primary school using epidemiological and genomic data.

ABSTRACT: Mathematical modelling studies have shown that repetitive screening can be used to mitigate SARS-CoV-2 transmission in primary schools while keeping schools open. However, not much is known about how transmission progresses within schools and whether there is a risk of importation to households. During the academic year 2020-2021, a prospective surveillance study using repetitive screening was conducted in a primary school and associated households in Liège (Belgium). SARS-CoV-2 screening was performed via throat washing either once or twice a week. We used genomic and epidemiological data to reconstruct the observed school outbreaks using two different models. The outbreaker2 model combines information on the generation time and contact patterns with a model of sequence evolution. For com

SUBMITTER: Kremer C 

PROVIDER: S-EPMC10273772 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature