The link between lymphocyte subpopulations in peripheral blood and metabolic variables in patients with severe obesity

ABSTRACT:

Background

Obesity, a public health problem, is a state of metainflammation that influences the development of chronic degenerative diseases, particularly in patients with severe obesity.

Objective

The objective of this study was to evidence immunometabolic differences in patients with different degrees of obesity, including severe obesity, by determining correlations between lymphocyte subpopulations and metabolic, body composition, and clinical variables.

Methods

Peripheral blood immune cells (CD4+, CD8+ memory and effector T lymphocytes) were analyzed, and measures of body composition, blood pressure, and biochemical composition (glucose, glycated hemoglobin (HbA1c), insulin, C-reactive protein (CRP), and the lipid profile) were carried out in patients with di

SUBMITTER: Rivera-Carranza T 

PROVIDER: S-EPMC10274585 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature