Cortical circuitry mediating inter-areal touch signal amplification.

ABSTRACT: Sensory cortical areas are often organized into topographic maps which represent the sensory epithelium^1,2. Individual areas are richly interconnected³, in many cases via reciprocal projections that respect the topography of the underlying map^4,5. Because topographically matched cortical patches process the same stimulus, their interaction is likely central to many neural computations^6-10. Here, we ask how topographically matched subregions of primary and secondary vibrissal somatosensory cortices (vS1 and vS2) interact during whisker touch. In the mouse, whisker touch-responsive neurons are topographically organized in both vS1 and vS2. Both areas receive thalamic touch input and are topographically interconnected⁴. Volumetric calcium

SUBMITTER: Ryan L 

PROVIDER: S-EPMC10274616 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature