Dengue in Cambodia 2002-2020: Cases, Characteristics and Capture by National Surveillance.

ABSTRACT:

Objective

Data from 19 years of national dengue surveillance in Cambodia (2002-2020) were analyzed to describe trends in dengue case characteristics and incidence.

Methods

Generalized additive models were fitted to dengue case incidence and characteristics (mean age, case phenotype, fatality) over time. Dengue incidence in a pediatric cohort study (2018-2020) was compared to national data during the same period to evaluate disease under-estimation by national surveillance.

Findings

During 2002-2020, there were 353,270 cases of dengue (average age-adjusted incidence 1.75 cases/1,000 persons/year) recorded in Cambodia, with an estimated 2.1-fold increase in case incidence between 2002 and 2020 (slope = 0.0058, SE = 0.0021, p = 0.006). Mean age of infected individuals in

SUBMITTER: Yek C 

PROVIDER: S-EPMC10274987 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature