Instruments measuring change in cognitive function in multiple sclerosis: A systematic review.

ABSTRACT:

Background

Multiple sclerosis (MS) is a chronic demyelinating/neurodegenerative disease associated with change in cognitive function (CF) over time. This systematic review aims to describe the instruments used to measure change in CF over time in people with MS (PwMS).

Methods

PubMed, OVID, Web of Science, and Scopus databases were searched in English until May 2021. Articles were included if they had at least 100 participants and at least a 1-year interval between baseline and last follow-up measurement of CF. Results were quantitatively synthesized, presented in tables and risk of bias was assessed with the Newcastle-Ottawa Scale.

Results

Fifty-seven articles met the inclusion criteria (41,623 PwMS and 1105 controls). An intervention (drug/rehabilitation) was assess

SUBMITTER: Ezegbe C 

PROVIDER: S-EPMC10275522 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature