Association of adverse childhood experiences with adulthood multiple sclerosis: A systematic review of observational studies.

ABSTRACT:

Introduction

Adverse childhood experiences (ACEs) are proposed to increase the risk of developing multiple sclerosis (MS) later in life. This systematic review aimed to explore the correlation between ACEs and MS development, age of onset, quality of life in MS patients and MS relapse rates.

Methods

We searched a total of six databases in June 2022 and retrieved the relevant studies. The population included adult (18+) individuals who either had been diagnosed or were at risk for developing MS and also had exposure to ACEs. Our primary outcomes include the risks of MS development, age of MS onset, and MS relapse rate in patients who were exposed to different types of ACEs.

Results

A total of 11 studies were included in our review. A study reported that among 300 women

SUBMITTER: Rehan ST 

PROVIDER: S-EPMC10275535 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature