Phylogenetic Analysis of Allotetraploid Species Using Polarized Genomic Sequences.

ABSTRACT: Phylogenetic analysis of polyploid hybrid species has long posed a formidable challenge as it requires the ability to distinguish between alleles of different ancestral origins in order to disentangle their individual evolutionary history. This problem has been previously addressed by conceiving phylogenies as reticulate networks, using a two-step phasing strategy that first identifies and segregates homoeologous loci and then, during a second phasing step, assigns each gene copy to one of the subgenomes of an allopolyploid species. Here, we propose an alternative approach, one that preserves the core idea behind phasing-to produce separate nucleotide sequences that capture the reticulate evolutionary history of a polyploid-while vastly simplifying its implementation by reducing a complex

SUBMITTER: Leal JL 

PROVIDER: S-EPMC10275558 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature