Sleep quality and temperament in association with autism spectrum disorder among infants in Japan.

ABSTRACT:

Background

Sleep problems and irritable temperaments are common among infants with autism spectrum disorder (ASD). The prospective association between such sleep problems and irritable temperaments and ASDs needs to be determined for elucidating the mechanism and exploring the future intervention study. Thus, in this study, we investigated whether sleep quality and temperament in 1-month-old infants are associated with the onset of ASD in 3-year-old children. We also assessed its sex-stratified associations.

Methods

We conducted a longitudinal study using data from 69,751 mothers and infants from a large-cohort study, the Japan Environment and Children's Study. We examined the prospective association between infant sleep quality and temperament at 1 month of age and ASD diag

SUBMITTER: Kikuchi K 

PROVIDER: S-EPMC10275966 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature