Enhanced liver Fibrosis® test predicts liver-related outcomes in the general population.

ABSTRACT:

Background & aims

The Enhanced Liver Fibrosis® (ELF) test exhibits good discriminative performance in detecting advanced liver fibrosis and in predicting liver-related outcomes in patients with specific liver diseases, but large population-based studies are missing. We analysed the predictive performance of the ELF test in a general population cohort.

Methods

Data were sourced from the Health 2000 study, a Finnish population-based health examination survey conducted in 2000-2001. Subjects with baseline liver disease were excluded. The ELF test was performed on blood samples collected at baseline. Data were linked with national healthcare registers for liver-related outcomes (hospitalisation, cancer, and death).

Results

The cohort comprised 6,040 individuals (mean age

SUBMITTER: Saarinen K 

PROVIDER: S-EPMC10276292 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature