Biomarkers as targets for CAR-T/NK cell therapy in AML.
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ABSTRACT:
SUBMITTER: Shao R
PROVIDER: S-EPMC10276424 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
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Biomarkers as targets for CAR-T/NK cell therapy in AML.
Shao Ruonan R Li Zijian Z Xin Honglei H Jiang Suyu S Zhu Yilin Y Liu Jingan J Huang Rong R Xu Kailin K Shi Xiaofeng X
Biomarker research 20230617 1
The most common kind of acute leukemia in adults is acute myeloid leukemia (AML), which is often treated with induction chemotherapy regimens followed by consolidation or allogeneic hematopoietic stem cell transplantation (HSCT). However, some patients continue to develop relapsed or refractory AML (R/R-AML). Small molecular targeted drugs require long-time administration. Not all the patients hold molecular targets. Novel medicines are therefore needed to enhance treatment outcomes. T cells and ...[more]
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