Cardiovascular mortality in patients with advanced chronic kidney disease with and without diabetes: a nationwide cohort study.

ABSTRACT:

Background

Cardiovascular mortality and the impact of cardiac risk factors in advanced chronic kidney disease (CKD) remain poorly investigated. We examined the risk of cardiovascular mortality in patients with advanced CKD with and without diabetes as well as the impact of albuminuria, plasma hemoglobin, and plasma low-density lipoprotein (LDL) cholesterol levels.

Methods

In a Danish nationwide registry-based cohort study, we identified persons aged ≥ 18 years with an estimated glomerular filtration rate < 30 mL/min/1.73m² between 2002 and 2018. Patients with advanced CKD were age- and sex-matched with four individuals from the general Danish population. Cause-specific Cox regression models were used to estimate the 1-year risk of cardiovascular mortality standard

SUBMITTER: Kofod DH 

PROVIDER: S-EPMC10276454 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature