A MATLAB-based app to improve LC-MS/MS data analysis for N-linked glycan peak identification.

ABSTRACT:

Background

Glycosylation is an important modification to proteins that plays a significant role in biological processes. Glycan structures are characterized by liquid chromatography (LC) combined with mass spectrometry (MS), but data interpretation of LC/MS and MS/MS data can be time-consuming and arduous when analyzed manually. Most of glycan analysis requires dedicated glycobioinformatics tools to process MS data, identify glycan structure, and display the results. However, software tools currently available are either too costly or heavily focused on academic applications, limiting their use within the biopharmaceutical industry for implementing the standardized LC/MS glycan analysis in high-throughput manner. Additionally, few tools provide the capability to generate report-rea

SUBMITTER: Dhingra A 

PROVIDER: S-EPMC10276461 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature