Shengxian decoction protects against chronic heart failure in a rat model via energy regulation mechanisms.

ABSTRACT:

Background

Chronic heart failure (CHF) is actually a disease caused by an imbalanced energy metabolism between myocardial energy demand and supply, ultimately resulting in abnormal myocardial cell structure and function. Energy metabolism imbalance plays an important role in the pathological process of chronic heart failure (CHF). Improving myocardial energy metabolism is a new strategy for the treatment of CHF. Shengxian decoction (SXT), a well-known traditional Chinese medicine (TCM) formula, has good therapeutic effects on the cardiovascular system. However, the effects of SXT on the energy metabolism of CHF is unclear. In this study, we probed the regulating effects of SXT on energy metabolism in CHF rats using various research methods.

Methods

High-performance liquid ch

SUBMITTER: Yang ZQ 

PROVIDER: S-EPMC10276516 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature