Prone position versus usual care in hypoxemic COVID-19 patients in medical wards: a randomised controlled trial.

ABSTRACT:

Background

Benefit of early awake prone positioning for COVID-19 patients hospitalised in medical wards and who need oxygen therapy remains to be demonstrated. The question was considered at the time of COVID-19 pandemic to avoid overloading the intensive care units. We aimed to determine whether prone position plus usual care could reduce the rate of non-invasive ventilation (NIV) or intubation or death as compared to usual care alone.

Methods

In this multicentre randomised clinical trial, 268 patients were randomly assigned to awake prone position plus usual care (N = 135) or usual care alone (N = 132). The primary outcome was the proportion of patients who underwent NIV or intubation or died within 28 days. Main secondary outcomes included the rates of NIV, of intubation

SUBMITTER: Nay MA 

PROVIDER: S-EPMC10276908 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature