Folate-mediated one-carbon metabolism as a potential antifungal target for the sustainable cultivation of microalga Haematococcus pluvialis.

ABSTRACT:

Background

Microalgae are widely considered as multifunctional cell factories that are able to transform the photo-synthetically fixed CO₂ to numerous high-value compounds, including lipids, carbohydrates, proteins and pigments. However, contamination of the algal mass culture with fungal parasites continues to threaten the production of algal biomass, which dramatically highlights the importance of developing effective measures to control the fungal infection. One viable solution is to identify potential metabolic pathways that are essential for fungal pathogenicity but are not obligate for algal growth, and to use inhibitors targeting such pathways to restrain the infection. However, such targets remain largely unknown, making it challenging to develop effective measur

SUBMITTER: Yan H 

PROVIDER: S-EPMC10276916 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature