Clinical use of remdesivir in COVID-19 treatment: a retrospective cohort study.

ABSTRACT:

Objectives

This study investigated remdesivir's clinical use to provide direct evidence of effectiveness for a low-middle income Asian setting.

Design

A one-to-one propensity score matching retrospective cohort study.

Setting

A tertiary hospital with COVID-19 treatment facilities in Vietnam.

Participants

A total of 310 patients in standard of care (SoC) group were matched with 310 patients in SoC+remdesivir (SoC+R) group.

Primary and secondary outcome measures

The primary outcome was time to critical progression, defined as all-cause mortality or critical illness. The secondary outcomes were length of oxygen therapy/ventilation and need for invasive mechanical ventilation. Outcome reports were presented as HR, OR or effect difference with 95% CI.

Resu

SUBMITTER: Pham HT 

PROVIDER: S-EPMC10276957 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature