A hypothesis - generating Swedish extended national cross-sectional family study of multimorbidity severity and venous thromboembolism.

ABSTRACT:

Objectives

Venous thromboembolism (VTE) is a common worldwide disease. The burden of multimorbidity, that is, two or more chronic diseases, has increased. Whether multimorbidity is associated with VTE risk remains to be studied. Our aim was to determine any association between multimorbidity and VTE and any possible shared familial susceptibility.

Design

A nationwide extended cross-sectional hypothesis - generating family study between 1997 and 2015.

Setting

The Swedish Multigeneration Register, the National Patient Register, the Total Population Register and the Swedish cause of death register were linked.

Participants

2 694 442 unique individuals were analysed for VTE and multimorbidity.

Main outcomes and measures

Multimorbidity was determined by a cou

SUBMITTER: Ahren J 

PROVIDER: S-EPMC10277039 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature