Early biomarkers of neurodevelopmental disorders in preterm infants: protocol for a longitudinal cohort study.

ABSTRACT:

Introduction

Preterm (PT) infants are at high likelihood for poor neurodevelopmental outcomes, including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and other neurodevelopmental disorders (NDDs), which could considerably impair the individuals' functions throughout their whole life. The current cohort study aims to investigate adverse outcomes, especially NDDs, in PT children, and the related early aberrant brain developmental biomarkers.

Methods and analysis

This is a prospective cohort study in Beijing, China. We plan to recruit 400 PT infants born at <37 weeks of gestational age (GA), and 200 full-term (FT) controls during the neonatal period (40 weeks corrected GA), then follow them up until they reach 6 years of age. This cohort is de

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC10277126 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature