Rheumatoid Arthritis Disease Activity and Hospitalized Infection in a Large US Registry.

ABSTRACT:

Objectives

The association between disease activity and infection risk among patients with rheumatoid arthritis (RA) is not clear, and it is challenging to determine because of confounding due to the effects of RA treatments and comorbidities.

Methods

Using patients with RA in the CorEvitas registry with Medicare coverage in 2006-2019, we identified eligible patients who had at least 1 visit with moderate disease activity based on the Clinical Disease Activity Index (CDAI; CDAI >10 and ≤22). Follow-up started at the subsequent CorEvitas visit. Hospitalized infection during follow-up was assessed in linked Medicare data. We calculated the incidence rate of hospitalized infection for patients in remission, and low and moderate disease activity, and estimated the effect of time

SUBMITTER: Yun H 

PROVIDER: S-EPMC10277216 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature