K^trans Calculation Using Reference Method Corrected Native T₁₀ for Breast Cancer Diagnosis.

ABSTRACT:

Purpose

The objective of the study is to use multiple tube phantoms to generate correction factor at different spatial locations for each breast coil cuff to correct the native T₁₀ value in the corresponding spatial location of the breast lesion. The corrected T₁₀ value was used to compute K^trans and analyze its diagnostic accuracy in the classification of target condition, i.e., breast tumors into malignant and benign.

Materials and methods

Both in vitro phantom study (external reference) and patient's studies were acquired on simultaneous positron emission tomography/magnetic resonance imaging (PET/MRI) Biograph molecular magnetic resonance (mMR) system using 4 channel mMR breast coil. The spatial correction factors derived using mul

SUBMITTER: Negi PS 

PROVIDER: S-EPMC10277302 | biostudies-literature | 2023 Jan-Mar

REPOSITORIES: biostudies-literature