The prevalence and risk of developing major depression among individuals with subthreshold depression in the general population.

ABSTRACT:

Background

Subthreshold depression could be a significant precursor to and a risk factor for major depression. However, reliable estimates of the prevalence and its contribution to developing major depression under different terminologies depicting subthreshold depression have to be established.

Methods

By searching PubMed and Web of Science using predefined inclusion criteria, we included 1 129 969 individuals from 113 studies conducted. The prevalence estimates were calculated using the random effect model. The incidence risk ratio (IRR) was estimated by measuring the ratio of individuals with subthreshold depression who developed major depression compared to that of non-depressed individuals from 19 studies (88, 882 individuals).

Results

No significant difference i

SUBMITTER: Zhang R 

PROVIDER: S-EPMC10277767 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature