Dataset Information

Cardiometabolic disease risk factors in pre- and postmenopausal women from four sub-Saharan African countries: A cross-sectional study.

ABSTRACT:

Objective

To compare the risk factors for cardiometabolic disease between pre- and postmenopausal women from four sub-Saharan African countries.

Study design

This cross-sectional study included 3609 women (1740 premenopausal and 1869 postmenopausal) from sites in Ghana (Navrongo), Burkina Faso (Nanoro), Kenya (Nairobi), and South Africa (Soweto and Dikgale). Demographic, anthropometric and cardiometabolic variables were compared between pre- and postmenopausal women, within and across sites using multivariable regression analyses. The sites represent populations at different stages of the health transition, with those in Ghana and Burkina Faso being rural, whilst those in Kenya and South Africa are more urbanised.

Main outcome measures

Anthropometric and cardiometabolic variables.

Results

The prevalence rates of risk factors for cardiometabolic disease were higher in South (Soweto and Dikgale) and East (Nairobi) Africa than in West Africa (Nanoro and Navrongo), irrespective of menopausal status. Regression models in combined West African populations demonstrated that postmenopausal women had a larger waist circumference (β = 1.28 (95 % CI: 0.58; 1.98) cm), log subcutaneous fat (β =0.15 (0.10; 0.19)), diastolic (β = 3.04 (1.47; 4.62) mm Hg) and log systolic (β = 0.04 (0.02; 0.06)) blood pressure, log carotid intima media thickness (β = 0.03 (0.01; 0.06)), low-density lipoprotein cholesterol (β = 0.14 (0.04; 0.23) mmol/L) and log triglyceride (β= 0.10 (0.04; 0.16)) levels than premenopausal women. No such differences were observed in the South and East African women.

Conclusions

Menopause-related differences in risk factors for cardiometabolic disease were prominent in West but not East or South African study sites. These novel findings should inform cardiometabolic disease prevention strategies in midlife women specific to rural and urban and peri-urban locations in sub-Saharan Africa.

SUBMITTER: Chikwati RP

PROVIDER: S-EPMC10278059 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Publications

Cardiometabolic disease risk factors in pre- and postmenopausal women from four sub-Saharan African countries: A cross-sectional study.

Chikwati Raylton P RP Mahyoodeen Nasrin Goolam NG Jaff Nicole G NG Ramsay Michele M Micklesfield Lisa K LK Wade Alisha N AN Agongo Godfred G Asiki Gershim G Choma Solomon S R SSR Boua Palwende R PR George Jaya A JA Crowther Nigel J NJ

Maturitas 20230420

<h4>Objective</h4>To compare the risk factors for cardiometabolic disease between pre- and postmenopausal women from four sub-Saharan African countries.<h4>Study design</h4>This cross-sectional study included 3609 women (1740 premenopausal and 1869 postmenopausal) from sites in Ghana (Navrongo), Burkina Faso (Nanoro), Kenya (Nairobi), and South Africa (Soweto and Dikgale). Demographic, anthropometric and cardiometabolic variables were compared between pre- and postmenopausal women, within and ac ...[more]

PMID: 37116348

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Dataset Information

Cardiometabolic disease risk factors in pre- and postmenopausal women from four sub-Saharan African countries: A cross-sectional study.

Objective

Study design

Main outcome measures

Results

Conclusions

Publications

Cardiometabolic disease risk factors in pre- and postmenopausal women from four sub-Saharan African countries: A cross-sectional study.

Similar Datasets

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