Altered whole-brain resting-state functional connectivity and brain network topology in typhoon-related post-traumatic stress disorder

ABSTRACT:

Background:

Altered resting-state functional connectivity has been found in patients with post-traumatic stress disorder (PTSD). However, the alteration of resting-state functional connectivity at whole-brain level in typhoon-traumatized individuals with PTSD remains largely unknown.

Objectives:

To investigate changes in whole-brain resting-state functional connectivity and brain network topology in typhoon-traumatized subjects with and without PTSD.

Design:

Cross-sectional study.

Methods:

Twenty-seven patients with typhoon-related PTSD, 33 trauma-exposed controls (TEC), and 30 healthy controls (HC) underwent resting-state functional MRI scanning. The whole brain resting-state functional connectivity network was constructed based on the automated anatomi

SUBMITTER:  

PROVIDER: S-EPMC10278414 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature