Individualized prediction of survival benefit from postoperative radiotherapy for patients with malignant pleural mesothelioma.

ABSTRACT:

Objectives

The role of postoperative radiotherapy (PORT) in malignant pleural mesothelioma (MPM) remains controversial and the eighth edition TNM staging scheme for MPM has not been fully verified. We aimed to develop an individualized prediction model for identifying optimal candidates for PORT among MPM patients who received surgery plus chemotherapy and externally validate the performance of the new TNM staging scheme.

Materials and methods

Detailed characteristics of MPM patients during 2004-2015 were retrieved from SEER registries. Propensity score matching (PSM) was conducted to reduce disparities of baseline characteristics (age, sex, histologic type, stage, and type of surgery) between the PORT group and no-PORT group. A novel nomogram was constructed based on indepe

SUBMITTER: Wo Y 

PROVIDER: S-EPMC10278470 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature