Impact of race/ethnicity and language preferences on pediatric ALL survival outcomes.

ABSTRACT:

Background

Ethnic and racial disparities have recently been observed both in treatment-related toxicities and rates of long-lasting cure in acute lymphoblastic leukemia (ALL) and acute lymphoblastic lymphoma (ALLy), the most common pediatric malignancy. Despite significant improvements in overall survival in the recent past, a large number of children die from aggressive disease.

Methods

We performed a retrospective cohort analysis of 274 pediatric ALL/ALLy patients within Montefiore Health System from 2004 to 2021 to determine differences in all-cause mortality within the Pediatric Hematologic Malignancies Cohort using Cox Proportional Hazard regression modeling, adjusted for age at diagnosis, race/ethnicity, administration of intensive chemotherapy, preferred language, max

SUBMITTER: Davitt M 

PROVIDER: S-EPMC10278473 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature