Investigating potential disparities in clinical trial eligibility and enrollment at an NCI-designated comprehensive cancer center.

ABSTRACT:

Background

Although barriers to trial accrual are well-reported, few studies have explored trial eligibility and trial offers as potential drivers of disparities in cancer clinical trial enrollment.

Methods

We identified patients with gastrointestinal (GI) or head/neck (HN) malignancies who were seen as new patients at the University of Michigan Health Rogel Cancer Center in 2016. By exhaustive review of the electronic medical record, we assessed the primary outcomes: (1) eligibility for, (2) documented offer of, and (3) enrollment in a clinical trial. All 41 of the clinical trials available to these patients were considered. Independent variables included clinical and non-clinical patient-related factors. We assessed associations between these variables and the primary outc

SUBMITTER: Patel MA 

PROVIDER: S-EPMC10278521 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature