Modelling the differential effects of age on transcranial magnetic stimulation induced electric fields.

ABSTRACT: Objective. The therapeutic application of noninvasive brain stimulation modalities such as transcranial magnetic stimulation (TMS) has expanded in terms of indications and patient populations. Often neurodevelopmental and neurodegenerative changes are not considered in research studies and clinical applications. This study sought to examine TMS dosing across time points in the life cycle.Approach. TMS induced electric fields with a figure-of-eight coil was simulated at left dorsolateral prefrontal cortex regions and taken in vertex as a control region. Realistic magnetic resonance imaging-based head models (N= 48) were concurrently examined in a cross-sectional study of three different age groups (children, adults, and elderlies).Main results. Age had a negative

SUBMITTER: Alawi M 

PROVIDER: S-EPMC10278869 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature