Comprehensive analysis of gut microbiome and host transcriptome in chickens after Eimeria tenella infection.

ABSTRACT:

Background

Coccidiosis is an intestinal parasitic disease caused by Eimeria protozoa, which endangers the health and growth of animals, and causes huge economic losses to the poultry industry worldwide every year. Studies have shown that poultry gut microbiota plays an important role in preventing the colonization of pathogens and maintaining the health of the host. Coccidia infection also affects host gene expression. However, the underlying potential relationship between gut microbiome and host transcriptome during E. tenella infection in chickens remain unclear.

Methods

In this study, metagenomic and transcriptome sequencing were applied to identify microbiota and genes in cecal contents and cecal tissues of infected (JS) and control (JC) chickens on day 4.5

SUBMITTER: Yu H 

PROVIDER: S-EPMC10279956 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature