The Neurophysiological Lesion: A Scoping Review.

ABSTRACT:

Objective

The purpose of this study was to examine the extent of the literature on the neurophysiological lesion as referenced in functional neurology.

Methods

A literature search was performed within the period from 2010 to March 2021. Search terms included central sensitization, central sensitivity syndrome, nociplastic pain, cold hyperalgesia, heat hyperalgesia, mechanical hyperalgesia, dynamic mechanical allodynia, temporal summation, spatial summation, and descending inhibition. A qualitative synthesis summarized the research findings, including clinical conditions and effect of spinal manipulation.

Results

There were 30 studies, which included 7 high-level studies (meta-analysis or systematic reviews), 22 randomized controlled studies, and 1 scoping review. The

SUBMITTER: Taylor DN 

PROVIDER: S-EPMC10280090 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature